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Grape compound increases
good fat hormone
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A compound in grapes displays antioxidant and
other positive properties. Now, a new study has described a novel way in which
resveratrol exerts these beneficial health effects.
Resveratrol stimulates the expression of adiponectin, a hormone derived from
cells that manufacture and store fat, the team found.
Adiponectin has a wide range of beneficial effects on obesity-related medical
complications, said senior author Feng Liu, professor of pharmacology and member
of the Barshop Institute of Longevity and Aging Studies at UT Health Science
Center San Antonio.
Both adiponectin and resveratrol display anti-obesity, anti-insulin resistance
and anti-aging properties.
"Results from these studies should be of interest to those who are obese,
diabetic and growing older," Dr. Liu said.
"The findings should also provide important information on the development of
novel therapeutic drugs for the treatment of these diseases."
The researchers confirmed the finding in cells and animal models.
The study appears in the Jan. 7 issue of the Journal of Biological Chemistry
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