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Breath
Test could help detect lung cancer
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ANI: Washington: Lung cancer may be detected in patients by testing their
exhaled breath, researchers have claimed.
Preliminary studies by researchers at Cleveland Clinic suggest that an accurate
exhaled breath biomarker could be developed for use as a clinical test.
"We
believe that cancer cells release a unique chemical signature related to the
tumor-growing process," Peter J. Mazzone, MD, FCCP, director of the lung cancer
program for the Respiratory Institute at Cleveland Clinic, said.
"We
are currently developing a breath-based test based on the results of our
research," he said
Dr. Mazzone and his colleagues studied 82 people with biopsy-confirmed lung
cancer who had not yet received treatment against a control group of 155 people
who were either at-risk for lung cancer or who had benign lung nodules.
Subjects were asked to breathe normally while their breath was exposed to a
high-dimensional chemical sensor called a colorimetric sensor array.
 The
colors on the array change when exposed to various chemicals. If the chemicals
in the breath contained markers for lung cancer, the array would show that in a
pattern of color changes.
The
colorimetric sensor array continually monitored the chemicals exhaled from the
breath of the subjects, resulting in sensor changes that accurately
distinguished the breath of people with lung cancer from the controls.
The
findings were presented at CHEST 2013 in Chicago, Illinois.
( Courtesy: Zee news .
read the article )
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