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Indian Scientists developed Insulin Pill for diabetics
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The Indian Scientists, National Institute of Pharmaceutical Education and
Research (NIPER) developed insulin pill for diabetics in third week of December
2013
The Scientists developed a long-sought insulin pill that could spare millions of
diabetics and soughed a way the delivery of insulin therapy from a jab to a
pill.
The experiments with rats, the pill lowered blood glucose levels almost as much
as injected insulin and the effects of the pill lasted longer than injected
insulin.
The body’s digestive enzymes in the body are so good at breaking down food also
break down insulin before it can get to work. In addition, insulin does not get
easily absorbed through the gut into bloodstream.
To solve these problem researchers from National Institute of Pharmaceutical
Education and Research (NIPER) in Punjab combined two approaches to shield
insulin from the digestive enzymes and then get it into the blood.
The team of researchers Ashish Kumar Agrawal, Harshad Harde, Kaushik Thanki and
Sanyog Jain, packaged insulin in tiny sacs made of lipids or fats called
liposome.Then wrapped the liposomes in layers of protective molecules called
polyelectrolytes.
To get absorbed and to transport the layersome across the intestinal wall into
the blood stream they attached folic acid and a kind of vitamin B.
This was published in American Chemical Society journal biomacromolecules,
Washington.
(
Courtesy:
http://www.jagranjosh.com )
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